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2025. 05. 21 -

R. Eimont, Who Creates Artificial Tissues, Becomes a PhD

Dr Romuald Eimont. Photo from personal archive
On 16 May, we welcomed another new PhD. Romuald Eimont, a chemist in the FTMC Department of Nanoengineering, defended his thesis ‘Synthesis and Nanofabrication of Biomimetic Hydrogels’. Scientific advisor: Dr Ramūnas Valiokas.
 
Congratulations to our colleague for his significant work and best wishes for further success in this development!
 
Romuald's dissertation is closely related to tissue engineering - scientific methods aimed at restoring and maintaining the normal function of injured or damaged tissues and organs through the use of biomimetic materials. Typically, constructs employed in tissue engineering comprise biomimetic scaffolds with embedded tissue cells, forming an organotypic culture.
 
The extracellular matrix (ECM) and its mechanical properties serve not only as a physical surface for cell growth but also play a pivotal role in regulating cellular functions during tissue regeneration, wound healing, and disease progression.
 
Current research, particularly in mechanobiology and filler biology, has been concentrating on unravelling how the mechanical environment of the ECM, both in vitro and in vivo, influences the cell behaviour and function. Synthetic materials that faithfully replicate the basic mechanical and biological properties of the native tissues are crucial for understanding this.
 
 
(A basic tissue engineering scheme in which cells isolated from an organism are multiplied and combined with a biomimetic scaffold to form a tissue-mimicking construct that can be implanted in the body. Illustration from the thesis of Dr Romualdas Eimontas, page 10)
 
"During my PhD, I studied how to create materials that imitate the natural environment of tissues - so-called biomimetic hydrogels. I was interested in how surface microstructures or specific peptide sequences can affect the behaviour of cells - whether they will attach better, how their shape and growth will change," says R. Eimont.
 
He is most pleased with the fact that he has been able to combine different fields, from materials synthesis to biological testing: "The hydrogels we created were not only stable, but they also influenced cell behaviour. It was particularly interesting to observe how the different structures change the shape of the cells, or how the cells behave when enclosed in the channels formed by the biomimetic hydrogels."
 
"Such materials can be useful for both biomedical companies and research laboratories - for example, in the development of alternative testing models for drugs or surfaces for growing cells. They can also contribute to reducing the use of animals in testing, and in the future, potentially contribute to tissue regeneration solutions," says the new PhD.
 
Info: FTMC
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