The ultimate goal of this project is to develop ultra-fast full-field optical coherent microscopy (FF-OCM) system that would be able to image deep in tissue, and therefore, help to improve diagnosis of the human eye diseases. FF-OCM is based on interferometric signal detection that can effectively image non-labelled structures deep inside biomedical samples. Currently, the fastest FF-OCM systems rely on illuminating sample with a swept laser source and detecting signal with an ultra-fast camera (used to capture ultra-slow-motion videos). Although FF-OCM has been successfully used in a range of biomedical applications, however, the imaging depth is compromised due to inefficient rejection of multiply scattered photons. During the PhD, various sample illumination and signal detection schemes will be investigated to enhance the rejection of such photons. To this end, multispot illumination and wavefront shaping will be employed using digital-micromirror devices (DMD) and spatial light modulators (SLM).
For more information, please contact the theme supervisor E.Auksorius.